Wondering about Watercress

Watercress contains significant amounts of iron, calcium and folic acid, in addition to vitamins A and C. Many health benefits are attributed to eating watercress

Although this blog isn’t chiefly about watercress, despite the name, I decided to explore it in several posts this year. I’m glad I did because I learned much I didn’t know and hope you did too.

In this post I’ve gathered the watercress posts in one place for your convenience. If you don’t want to read all of them now, bookmark this page so you can come back to it.

Nasturtium officinale W.T. Aiton - watercress NAOF

What is watercress? It depends on who you ask.

Watercress contains significant amounts of iron, calcium and folic acid, in addition to vitamins A and C. Many health benefits are attributed to eating watercress , such as that it acts as a mild stimulant, a source of phytochemicals and antioxidants, a diuretic, an expectorant, and a digestive aid. It may also have cancer-suppressing properties, and is widely believed to help defend against lung cancer.

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Native American pottery

How Native Americans use watercress

Knowing that indigenous Americans understood and used plants in a variety of ways , I wondered if and how they might have used watercress. Watercress came to this continent from Europe and is now well established.

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exploring the HEART of watercress

I appreciate all of you who are following Watercress Words, and if you aren’t I invite you to join the wonderful people who are. You can meet some of them in the sidebar, where you can click on their image and visit their blogs. Use the form to get an email notification of new posts. Don’t worry, you won’t get anything else from me.

And I always appreciate your sharing this and all my posts on social media and linking to it on your blog and newsletters. Just please don’t use it as medical advice or recommendation, it’s for information and inspiration as we explore the HEART of health.

a cup of coffee surrounded by fall leaves

Dr Aletha

THE MUTANT PROJECT-a book review

At the same time, some of the more entrepreneurial see the potential for using genetic modification to selectively breed desirable and profitable human traits-high IQ, increased muscle mass, or designer skin color, and enhanced fertility, including choosing the gender of babies.

THE MUTANT PROJECT

Inside the global race to genetically modify humans

By Eben Kirksey

If this were the title of a fiction book, you might expect the main characters to be brilliant but misguided scientists, funded by biotech start-ups who see potential for massive profits by developing methods to manipulate human DNA. The applications of such technology for the treatment of genetic diseases, cancers, and viral infections could be worth billions of dollars.

At the same time, some of the more entrepreneurial see the potential for using genetic modification to selectively breed desirable and profitable human traits-high IQ, increased muscle mass, or designer skin color, and enhanced fertility, including choosing the gender of babies.

You would be right except The Mutant Project is not fiction; it is based on facts, meticulously researched by Eben Kirksey, Ph.D. In this book, Dr. Kirksey chronicles his travels around the world as he learned about genetic modification using CRISPR by interviewing multiple scientists and investors who were involved in the first genetically edited babies born in 2018.

The Mutant Timeline

One does not need a graduate degree in genetics to understand this book, although I am sure it would help. But here are some basic facts that introduce the book.

1818-Frankenstein by Mary Shelley, the world’s first science fiction book, about a young researcher fwho produces a creature with superhuman powers

1901-Hugo de Vries writes The Mutation Theory, about foundational ideas about genetic variation

1953- Watson and Crick are credited with discovering the DNA’s double helix structure

graphic depiction of DNA- the double helix

1978- Louise Brown is born, the world’s first “test-tube” baby

1987-CRISPR is discovered

a drawing representing CRISPR
CRISPR-Cas9 is a customizable tool that lets scientists cut and insert small pieces of DNA at precise areas along a DNA strand. This lets scientists study our genes in a specific, targeted way. Credit: Ernesto del Aguila III, National Human Genome Research Institute, NIH

2000-President Bill Clinton reveals preliminary findings from the Human Genome Project

2016-the first CRISPR clinical trial in the United States secures government approval

2016-The China National GeneBank opens, the goal is to collect DNA from every human on earth

CRISPR

CRISPR, “clustered interspaced short palindromic repeats” was discovered in bacteria in 1987, its purpose initially unknown. By 2012 scientists Jennifer Doudna and Emmanuelle Charpentier demonstrated how to modify human DNA with CRISPR. It is an enzyme that can “generate mutants by chopping up DNA.”

CRISPR/CAS9 systems allow scientists to make targeted changes to an organism's DNA
CRISPR/CAS9 systems allow scientists to make targeted changes to an organism’s DNA This image is excerpted from a U.S. GAO report: http://www.gao.gov/products/GAO-20-478SP

Even though Dr. Kirksey is reporting as a journalist, he makes it clear that he agrees with those who feel this technology must be approached cautiously, as there is a clear risk that “biotech companies may put profits ahead of patients.”

The chief protagonist of this saga is Dr. Jiankui He of China, the physician scientist responsible for modifying two embryos, creating the first edited babies in the world, twin girls born in China in October 2018. He believed he has assured his place in history by using CRISPR to make these embryos resistant to HIV (human immunodeficiency virus).

Such a technique could change the world, potentially making all humans resistant to this infectious disease which is deadly without treatment. How Dr. He went from “powerful scientific entrepreneur to pariah” within a few short years is both riveting and disappointing.

This story moves at a rapid pace as the author travelled around the world attending lectures and interviewing multiple people in varied locations; I suggest not laying the book aside once you start, as I found it easy to get lost. A background in basic biology is helpful but not necessary to enjoy this book, since the ethical and moral issues it raises go beyond the realm of science.

A nice feature of the book-it is dedicated to the twin girls, Lulu and Nana, who live in China with their parents and are reported to be healthy.

Thanks to St. Martin’s Press and NetGalley for a digital galley copy in exchange for my honest review.

other books by Dr. Kirksey

Freedom in Entangled Worlds

The Multispecies Salon

Emergent Ecologies

And if you enjoy video

Human Nature-documentary movie

Human Nature is a provocative exploration of CRISPR’s far-reaching implications, through the families it’s affecting, and the bioengineers who are testing its limits. How will this new power change our relationship with nature? What will it mean for human evolution? To answer these questions we must look back billions of years and peer into an uncertain future.

Unnatural Selection-documentary television series

From eradicating disease to selecting a child’s traits, gene editing gives humans the chance to hack biology. Meet the real people behind the science.

available on Netflix

exploring the HEART of health and genetics

I hope you will consider reading Dr. Kirksey’s book and watching some of the videos. The medical sciences are finding more and more uses for genetics, for example the mRNA vaccines developed to prevent COVID-19 infection. As Dr. Kirksey described in the book, there are significant ethical implications that bear watching.

I appreciate all of you who are following Watercress Words, and if you aren’t I invite you to join the wonderful people who are. You can meet some of them in the sidebar, where you can click on their image and visit their blogs. Use the form to get an email notification of new posts. Don’t worry, you won’t get anything else from me.

Dr. Aletha

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